The current grant seeks to expand the technology to explore actively targeted dendrimers or antibody targeted drug conjugates (ADCs) based on dendrimers, with a view to advancing these into the clinic. This broader collaboration will employ a range of synthetic biology approaches to probe the relationship between dendrimer structure and targeting efficiency and will lay the foundation for the design of next generation targeted dendrimers.
Professor Porter commented, “This program is a great example of the power of a successful academic-industry collaboration and the impact that can be derived from enduring relationships with synergistic skills. The team at Starpharma are fantastic collaborators and I am both delighted and grateful to Starpharma and the ARC, to receive this funding via the Linkage scheme. It will broaden and expedite the program and I look forward to the high impact outcomes it will undoubtedly generate”.
Dr Jackie Fairley, Starpharma CEO commented: “We are very pleased that this program has been awarded the ARC linkage grant and to continue working with MIPS towards the development of next-generation nanomedicines. Our work with targeted drug delivery is a particularly exciting, given that Antibody Drug Conjugates (ADCs) have been the feature of several significant commercial deals in 2020. Multiple studies have demonstrated that Starpharma’s DEP® technology provides enhanced therapeutic benefits to ADCs and we look forward to advancing these ADC programs and potential commercial discussions”.
The ARC’s Linkage Projects promote research partnerships between researchers, business, industry, community organisations and other publicly funded research agencies to find real-world solutions that benefit Australians. The Linkage funding scheme aims to encourage cooperative approaches to research and improve the use of research outcomes by strengthening links within Australia’s innovation industry.
The recently announced collaborative research projects will examine current issues ranging from how smartphone apps might help separated families, to developing solutions for low-income renters to better access solar energy, improving agricultural efficiency and looking at ways recycled materials might be used to build roads.