Important paper on proposed guidelines to improve the quality and reproducibility of bio-nano material studies – published in Nature Nanotechnology
Publications | September 21, 2018

CBNS members published an important paper on proposed guidelines to improve the quality and reproducibility of bio-nano material studies in the journal Nature Nanotechnology. This paper was a picture-perfect example for collaborative work among CBNS members and collaborating partners. Dr Matt Faria was the main author of the paper titled Minimum information reporting in bio-nano experimental literature and it was co-authored by the following CBNS member and alumni: CBNS alumni Mattias Björnmalm, CBNS CI Associate Professor Kris Thurecht, CBNS CI Professor Stephen Kent, CBNS CI Professor Rob Parton, CBNS CI Professor Maria Kavallaris, CBNS CI Dr Angus Johnston, CBNS CI and Node Leader Professor Justin Gooding, CBNS CI Dr Simon Corrie, CBNS CI Professor Ben Boyd, CBNS CI Professor Pall Thordarson, CBNS CI and Node Leader Professor Andrew Whittaker, CBNS PI Professor Molly Stevens, CBNS CI Professor Clive Prestidge, CBNS CI Professor Chris Porter, 2017 CBNS Visiting Professor Professor Wolfgang Parak, CBNS Director Professor Tom Davis, CBNS CI Professor Edmund Crampin and CBNS Deputy Director Professor Frank Caruso.

 

Abstract

Studying the interactions between nanoengineered materials and biological systems plays a vital role in the development of biological applications of nanotechnology and the improvement of our fundamental understanding of the bio–nano interface. A significant barrier to progress in this multidisciplinary area is the variability of published literature with regards to characterizations performed and experimental details reported. Here, we suggest a ‘minimum information standard’ for experimental literature investigating bio–nano interactions. This standard consists of specific components to be reported, divided into three categories: material characterization, biological characterization and details of experimental protocols. Our intention is for these proposed standards to improve reproducibility, increase quantitative comparisons of bio–nano materials, and facilitate meta analyses and in silico modelling.