New paper out! Marvin Wang’s review on nanoparticle-proteome in vitro and in vivo
Publications | August 1, 2018

PhD student Marvin Wang published a review in the Journal of Materials Chemistry B titled Nanoparticle-Proteome In Vitro and In Vivo. This is collaborative work together with Dr Johan GustafssonMs Emily PilkingtonDr Aleksandr KakinenMr Ibrahim JavedMs Ava Faridi,  CBNS Director Professor Tom Davis and Dr Pu Chun Ke.

 

Abstract

The protein corona is a concept central to a range of disciplines exploiting the bio-nano interface. As literature continues to expand in this field, it is essential to condense and contextualize the in vitro and in vivo proteome databases accumulated over the past decade: a goal which this review intends to achieve for the benefit of nanomedicine and nanobiotechnology. The parameters used for our review are the physicochemical characteristics of the nanoparticles, their surface ligands, the biological matrix from which a corona was formed, methods employed, plus the top-ten enriched corona proteins. In addition, the protein coronal networks and their implications in vivo are highlighted for selected studies.