Chris is Professor of Pharmaceutics at the Monash Institute of Pharmaceutical Sciences and Director, Monash Institute of Pharmaceutical Sciences. Chris’ group works to address the poor oral absorption of drugs with intrinsically low water solubility, and to develop delivery systems to enhance the activity and reduce the toxicity of anti-cancer agents.
Research Interests:
Publication | Year | Authors |
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Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability | 2016 | Hu, L,; Quach, T.; Han, S.; Lim, S. F.; Yadav, P.; Senyschyn, D.; Trevaskis, N. L.; Simpson, J. S.; Porter, C. J. |
Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo | 2015 | Müllner, M., Dodds, S.J., Nguyen, T.-H., Senyschyn, D., Porter, C.J.H., Boyd, B.J., Caruso, F. |
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief | 2017 | Jensen DD, Lieu T, Halls ML, Veldhuis NA, Imlach WL, Mai QN, Poole DP, Quach T, Aurelio L, Conner J, Herenbrink CK, Barlow N, Simpson JS, Scanlon MJ, Graham B, McCluskey A, Robinson PJ, Escriou V, Nassini R, Materazzi S, Geppetti P, Hicks GA, Christie MJ, Porter CJH, Canals M, Bunnett NW |
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy | 2017 | To E.E., Vlahos R., Luong R., Halls M.L., Reading P.C., King P.T., Chan C., Drummond G.R., Sobey C.G., Broughton B.R.S., Starkey M.R., Van Der Sluis R., Lewin S.R., Bozinovski S., ONeill L.A.J., Quach T., Porter C.J.H., Brooks D.A., OLeary J.J., Selemidis S. |
From sewer to saviour-targeting the lymphatic system to promote drug exposure and activity | 2015 | Trevaskis N.L., Kaminskas L.M., Porter C.J.H. |