Professor Robert Parton
Chief Investigator
University of Queensland

Biography

Rob is a group leader in the Cell Biology and Molecular Medicine Division of the Institute for Molecular Biosciences and Deputy Director of the Centre for Microscopy and Microanalysis.

Rob is studying the function of caveolae; small ‘pockets’ on the plasma membrane that form specialised domains of the cell surface with a distinct structure and function. Defective caveolae in human patients are associated with cancer, lipodystrophies (lack of fat tissue), muscular dystrophy, and cardiovascular disease. He is also investigating the use of bacterial ‘caveolae’ in drug delivery and vaccine development.

Signature Projects

Professor Parton is currently actively investigating within the following Signature Projects:

Featured Publications

PublicationYearAuthors
An endosomal tether undergoes an entropic collapse to bring vesicles together2016Murray, D.H.; Jahnel, M.; Lauer, J.; Avellaneda, M.J.; Brouilly, N.; Cezanne, A.; Morales-Navarrete, H.; Perini, E.D.; Ferguson, C.; Lupas, A.N.; Kalaidzidis, Y.; Parton, R.G.; Grill, W.S.; Zerial M.
Cell polarity defines three distinct domains in pancreatic beta cells2016Gan, W.J.; Zavortink, M.; Ludick, C.; Templin, R.; Webb, R.; Webb, R.; Ma, W.; Poronnik, P.; Parton, R.G.; Gaisano, H.Y.; Shewan, A.M.; Thorn, P.
Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination2016Pageon, S.V.; Tabarin, T.; Yamamoto, Y.; Ma, Y.; Bridgeman, J.S.; Cohnen, A.; Benzing, C.; Gao, Y.; Crowther, M.D.; Tungatt, K.; Doltonc, G.; Sewellc, A.K.; Pricec, D.A.; Acutoe, O.; Partong, R.G.; Gooding, J.J.; Rossya, J.; Rossjohnc, J.; Gausa, K.
Human immune cell targeting of protein nanoparticles-caveospheres2016Glass, J.J.; Yuen, D.; Rae, J.; Johnston, A.P.; Parton, R.G.; Kent, S.J.; De Rose, R.
Unraveling the architecture of caveolae2016Parton, R.G.; Collins, B.M.

Collaborations