Entries for The Science by Design Competition have now concluded and it is your time to vote for your favourite!
All CBNS members are able to vote for their favourite design. The winner of the People’s Choice Award will receive a gift card worth $50 and will be invited to receive their award at the 2019 CBNS Annual Research Workshop, with the cost of accommodation to be covered by CBNS. The CBNS will feature the People’s Choice Award winner in the 2019 Annual Report, along with the overall winner, with attribution to the creators.
The judging period starts today and concludes at 7:00 pm on 1 November.
- The creativity of the design – How unique is the design?
- Use of design elements
- Ingenuity – degree of tricks used
- The effectiveness of science communication – How easy is it for you to grasp the concept of the artist’s work?
Voting is easy – just read through the summaries and then pick your favourite from the below:
Entry 1: Mechanism of focused ultrasound-induced blood-brain barrier disruption.
My work focuses on the study of the effects of tumour vasculature remodelling by focused ultrasound on the delivery of tumour-targeting antibodies in a mouse model of higher grade gliomas, by use of multimodal imaging techniques, including PET/CT/MRI and optical imaging.
Entry 2: Interaction of nanoparticles and drug with gut cells: a key to successful oral delivery system
The oral application of pharmaceuticals is unarguably the most convenient method of application. Understanding the interaction nanoparticles, small molecules and proteins with the enterocytes in the gut. Exploring this interaction would help to develop effective oral drug delivery systems.
Entry 3: On the hunt for a global disease: Proteomic and transcriptomic profiling of placental extracellular vesicles in preeclampsia
The image illustrates our systematic approach to decipher molecular mechanisms of preeclampsia and, ultimately, to identify early biomarkers. Extracellular vesicles (EVs) are secreted by placental cells including syncytiotrophoblastic cells and their isolation using an immunocapture microfluidic device will allow to establish for the first time their proteomic and transcriptomic profiles.
Entry 4: High-density lipoprotein nanoparticles; A natural taxi for radio-sensitizing miRNAs
High density lipoprotein (HDL) nanoparticles are promising delivery systems for radio-sensitizing miRNAs. HDL based delivery modifies the pharmacokinetics of its RNA payload and increase uptake by tumour cells. We anticipate that this strategy will reduce off-target miRNA effects while potentiating radio-sensitizing effects.
Entry 5: A Metabolic Labelling Based Approach for Highly Selective Gastrointestinal Delivery
Metabolic glycan-labelling is a technique to modify functional groups present on the cell surface by intruding the natural glycosylation pathway. Click chemistry describes two complementary functional groups that react exclusively and covalently with each other in mild conditions. The design shows the combination of metabolic labelling and click chemistry to enable targeting of functionalised drug carrier or dye to modified cells.